NEWS-RESEARCH AND INDUSTRY

• PIONEER 5: Oral Semaglutide for Diabetes With Moderate CKD June 24, 2019
  SAN FRANCISCO — In patients with both type 2 diabetes and moderate chronic kidney disease (CKD), the investigational oral glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide (Novo Nordisk) ...
• The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations June 24, 2019
  Glucagon and insulin maintain blood glucose homeostasis and are used to treat hypoglycemia and hyperglycemia, respectively, in patients with diabetes. Whereas insulin is stable for weeks in its ...
• Chemists discover structure of glucagon fibrils June 24, 2019
  "Peptide fibrillization is a problem that the pharmaceutical industry has been working for many years to solve." Using nuclear magnetic resonance (NMR) spectroscopy, the researchers found that the ...
• Simultaneous assay for protease activities of hepatitis C virus and human immunodeficiency virus based on fluorescence detection June 24, 2019
  In this study, a novel assay was developed to determine HCV-PR activity. This assay is based on a fluorogenic reaction, in which peptide fragments generated from an acetyl peptide substrate by HCV-PR ...
• Aileron Therapeutics Strengthens Board of Directors with Appointments of William T. McKee and Josef H. von Rickenbach June 24, 2019
  Mr. McKee commented, “I am excited about the prospects for ALRN-6924, and the broad applicability of Aileron’s stabilized cell-permeating peptide platform. I look forward to working with the ...
• Steven Wright on the Bradfo Sho: 'The trust is going to have to be earned back' June 23, 2019
  In an exclusive interview with the Bradfo Sho podcast Red Sox pitcher Steven Wright revealed his life since he was suspended 80 games for Growth Hormone Releasing Peptide 2, including his address to ...
• Prebiotic supplement increases C-peptide levels in children with type 1 diabetes June 19, 2019
  “Prebiotics may be beneficial in children with type 1 diabetes by altering their intestinal microbiome,” Carol Huang, MD, PhD, FRCPC, associate professor in the department of pediatrics and ...
• Artificial peptide bond formation provides clues to creation of life on Earth June 18, 2019
  The main constituents of cells, tissue, organs, and whole organisms are proteins, which are built by the addition of amino acids one after another to form long protein chains called polypeptides. ...
• 2019 Competition News Global Glucagon Like Peptide-1 (GLP-1) Agonists Market Top Players, Trends and Forecast to 2028 June 16, 2019
  Jun 17, 2019 (WiredRelease via COMTEX) -- A Comprehensive research study manages by Market.us on “Global Glucagon Like Peptide-1 (GLP-1) Agonists Industry 2019” is an extensive, professional analysis ...
• New robust and efficient methods for the production of new peptide drugs June 12, 2019
  Many important natural products such as antibiotics, immunosuppressants, or anti-cancer drugs are produced by microorganisms. These natural products are often small peptides, which in several cases ...
• What's the Next Big Thing in the Peptide Therapeutics Market? Eli Lilly and Company, AstraZeneca Plc, Merck & Co., Inc., Ipsen S.A, Novo Nordisk A/S June 12, 2019
  Valley Cottage, NY -- (SBWIRE) -- 06/12/2019 -- Future Market Insights' latest market study on peptide therapeutics reports that peptide therapeutics is potentially a large market and is expanding ...
• How Japan’s Biggest Biotech Is Pioneering New Peptide-Based Drugs June 10, 2019
  What if we could take a library of trillions of molecules to create a new generation of medicines offering unprecedented power in fighting diseases like cancer? That’s exactly what Japan’s biggest ...